Revista CEFAC
https://revistacefac.org.br/article/doi/10.1590/1982-0216/201921313717
Revista CEFAC
Review Articles

Neonatal hearing screening of newborns of mothers with Diabetic Mellitus and/or hypertension in pregnancy: a systematic literature review

Triagem auditiva de neonatos de mães com Diabetes Mellitus e/ou hipertensão na gestação: uma revisão sistemática da literatura

Luíza Silva Vernier; Carla Thamires Rodriguez Castelli; Daniela Centenaro Levandowski

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Abstract

Purpose: to investigate the results of the Neonatal Hearing Screening (NHS) in neonates whose mothers presented hypertension and/or diabetes mellitus in their pregnancy.

Methods: a systematic review of the literature, without restriction of year and language, guided by the PRISMA protocol, that was carried out through a search in the MEDLINE (PUBMED), LILACS (BVS), SCOPUS, WEB OF SCIENCE and EMBASE databases, using neonatal screening AND hearing AND (hypertension OR diabetes mellitus) as descriptors. Studies that were duplicated or were unavailable were excluded.

Results: 64 records were found, 5 being included for analysis. These articles had been published in the last 13 years, originated from different countries, and using a retrospective (cross-sectional, n=1, case-control, n=1) or prospective design (cross-sectional, n=1, case-control, n=1; cohort, n=1). The findings of the articles demonstrated differences regarding the presence of changes in the NHS outcomes of newborns whose mothers presented hypertension and/or diabetes during pregnancy.

Conclusion: since the review showed contradictory results regarding changes in the NHS outcomes in the presence of mothers' hypertension and/or diabetes during pregnancy, prospective cohort studies are needed, in different contexts, in order to isolate confounding factors for hearing loss and minimize measurement bias and selection.

Keywords

Neonatal Screening; Hearing; Hypertension; Diabetes Mellitus; Review

Resumo

Objetivos: investigar os resultados da Triagem Auditiva Neonatal (TAN) em neonatos cujas mães tiveram hipertensão e/ou diabetes mellitus na gestação.

Métodos: revisão sistemática da literatura, sem restrição de ano e de idioma, guiada pelo protocolo PRISMA, realizada a partir de consulta às bases MEDLINE(PUBMED), LILACS(BVS), SCOPUS, WEB OF SCIENCE e EMBASE, utilizando-se os descritores neonatal screening AND hearing AND (hypertension OR diabetes mellitus). Foram excluídos estudos duplicados ou indisponíveis na íntegra.

Resultados: foram encontrados 64 registros, dos quais 5 foram incluídos para análise. Os artigos analisados foram publicados nos últimos 13 anos, originaram-se em diferentes países e apresentaram tanto delineamento retrospectivo (transversal, n=1; caso-controle, n=1) como prospectivo (transversal, n=1; caso-controle, n=1; coorte, n=1). Os achados dos estudos revisados demonstram divergências quanto à presença de alterações no resultado da TAN de recém-nascidos cujas mães apresentaram hipertensão e/ou diabetes gestacional.

Conclusão: diante dos resultados contraditórios a respeito de alterações do resultado da TAN na presença de hipertensão e/ou diabetes na gestação, sugere-se a realização de estudos de coorte prospectivos, em diferentes contextos, a fim de isolar os fatores de confusão para perda auditiva e minimizar os vieses de aferição e seleção.

Palavras-chave

Triagem Neonatal; Audição; Hipertensão; Diabetes Mellitus; Revisão

References

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Submitted date:
09/11/2018

Accepted date:
12/19/2018

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